1. Home
  2. Bio-Reign®

Description and Intended Use

Bio-Reign® Bioactive is composed of anorganic bone mineral, bioactive glass, and type I collagen that can be molded to fit the bone defect. It is an osteoconductive, bioactive, porous implant that allows for bony ingrowth across the graft site. The bone graft matrix is slowly resorbed and replaced by new bone tissue during the healing process.

Bio-Reign® Bioactive combined with either autogenous bone marrow or autograft with saline is indicated for bony voids or gaps, that are not intrinsic to the stability of the bony structure. Bio-Reign® Bioactive can also be used with autograft as a bone graft extender.

The device is to be gently packed into bony voids or gaps of the skeletal system (i.e., posterolateral spine). These defects may be surgically created osseous defects or osseous defects created from traumatic injury to the bone. The device resorbs and is replaced with bone during the natural healing process.

Carbonate Apatite Anorganic Bone Mineral
Type I Collagen
45S5 Bioactive Glass

Ordering Information

  • Code Description
  • BR-025 Bio-Reign® Bioactive Moldable Bone Graft Matrix 2.5cc Strip
  • BR-05 Bio-Reign® Bioactive Moldable Bone Graft Matrix 5cc Strip
  • BR-010 Bio-Reign® Bioactive Moldable Bone Graft Matrix 10cc Strip

About Royal

Royal is a pioneering leader in orthobiologic and wound care research and development. Royal’s commitment lies in delivering top-tier, innovative biologic solutions that enhance the healing process and improve patients' quality of life. Royal places patient well-being at the center of its mission, offering exceptional solutions to address a variety of complex needs.

At Royal, our mission is driven by patient-centered care, innovation and excellence, and integrity and compassion.
Royal provides a comprehensive array of products tailored to meet the varied needs of the orthobiologic and wound care industry.

As a rapidly expanding force in the industry, Royal is continuously developing and launching new products and solutions that set benchmarks for quality, effectiveness, and patient outcomes. Royal’s commitment to research and innovation keeps it at the forefront of the industry, helping to shape the future of healthcare and improving lives.