Bio-Reign® 3D is a resorbable bone void filler intended to fill bony voids or gaps of the extremities and pelvis. It is radiolucent and composed of hyper crosslinked carbohydrate polymer with a total porosity of greater than 75%. Pores are mainly distributed within a range of 100-500 μm. When placed in direct contact with patient’s bone, Bio-Reign® 3D supports and guides the ingrowth of new bone across the graft site and is resorbed as the healing process occurs. The consistency of Bio-Reign® 3D allows the surgeon to easily manipulate and maximize its direct contact with viable host bone.

Bio-Reign® 3D is indicated for use only in the treatment of bony voids or gaps that are not intrinsic to the stability of the bony structure. It is intended to be gently packed into bony voids or gaps of the skeletal system (i.e., extremities and pelvis) with the opening to the defect site sealed with bone wax. These defects may be surgically created osseous defects or osseous defects created from traumatic or degenerative injury to the bone.