1. Home
  2. Bio-Reign®

The evolution of our mineral and collagen composite bone grafts has advanced with the launch of our unique bioactive glass, mineral, and collagen composite bone graft solutions. Bio-Reign® Bioactive bone graft matrices are a combination of three components: carbonate apatite anorganic bovine bone mineral, 45S5 bioactive glass, and Type I Collagen. When combined, they provide an optimal scaffold to support the body’s natural ability to regenerate new bone.

Bio-Reign® Bioactive Moldable is a bioactive, osteoconductive porous implant that supports an ideal environment for bone growth regeneration.

BIO-REIGN® INDICATION FOR USE

  • Combined with either autogenous bone marrow or autograft with saline is indicated for bony voids or gaps, that are not intrinsic to the stability of the bony structure. Bio-Reign® Bioactive Moldable can also be used with autograft as a bone graft extender.
  • The device is to be gently packed into bony voids or gaps of the skeletal system (i.e., posterolateral spine). These defects may be surgically created osseous defects or osseous defects created from traumatic injury to the bone. The device resorbs and is replaced with bone during the natural healing process.

OPTIMAL COMPONENTS

Carbonate Apatite Anorganic Bovine Bone Mineral, 45S5 Bioactive Glass, Highly Purified Type I Collagen
Carbonate Apatite Anorganic Bone Mineral
Type I Collagen
45S5 Bioactive Glass

Natural Mineral Structure

Porous, and a better osteoconductive material than HA1

Resorption & Remodeling

Similar to human bone2,3

Surface Potential

More Calcium Phosphate deposition than β-TCP4

2 FOR 1 VERSATILITY

Upon hydration, the strip can be used in its original shape or molded into alternative shapes.

Explore our Entire Product Line

About Royal

Royal is a pioneering leader in orthobiologic and wound care research and development. Royal’s commitment lies in delivering top-tier, innovative biologic solutions that enhance the healing process and improve patients' quality of life. Royal places patient well-being at the center of its mission, offering exceptional solutions to address a variety of complex needs.

At Royal, our mission is driven by patient-centered care, innovation and excellence, and integrity and compassion.
Royal provides a comprehensive array of products tailored to meet the varied needs of the orthobiologic and wound care industry.

As a rapidly expanding force in the industry, Royal is continuously developing and launching new products and solutions that set benchmarks for quality, effectiveness, and patient outcomes. Royal’s commitment to research and innovation keeps it at the forefront of the industry, helping to shape the future of healthcare and improving lives.